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CURATED PRIMARY SOURCES

Read the evidence.
Not the headline.

A growing index of peer-reviewed studies and official trial records, organised by molecule and evidence level — with clear boundaries between human data, registered protocols and preclinical research.

08primary records 03molecule groups 04languages
EVIDENCE MAPCURATED · AUG 2026
RESEARCH QUESTIONWhat type of evidence is this?
HUMAN DATA TRIAL RECORD PRECLINICAL

The evidence level describes the source design. It does not establish the quality, identity or suitability of a specific product.

SEARCH THE SOURCE, NOT THE CLAIM

Research records

Search by molecule, study or identifier. Filters describe study design — not a product rating or recommendation.

EVIDENCE TYPE
MOLECULE
08 records shownPRIMARY OR OFFICIAL SOURCES ONLY
HUMAN · PHASE 2 RCT

Retatrutide

Triple-hormone-receptor agonist retatrutide for obesity

New England Journal of Medicine · PMID 37366315

A randomised, double-blind phase 2 trial in adults with obesity. This is human efficacy and safety evidence for the investigational molecule under the study protocol.

Human evidenceOpen PubMed
HUMAN · SUBSTUDY

Retatrutide

Retatrutide and liver fat in adults with obesity

Nature Medicine · PMID 38858523

A phase 2 substudy using imaging endpoints to assess liver-fat changes. The finding belongs to the studied population, intervention and follow-up period.

Human evidenceOpen PubMed
OFFICIAL TRIAL RECORD

Retatrutide

TRIUMPH-3: obesity and cardiovascular disease

ClinicalTrials.gov · NCT05882045

An official phase 3 study record describing the protocol, endpoints and current status. A registry record must be read separately from company announcements and later peer-reviewed publications.

Registered protocolOpen registry
HUMAN · PHASE 3 RCT

Tirzepatide

SURMOUNT-1: tirzepatide once weekly for obesity

New England Journal of Medicine · PMID 35658024

A 72-week randomised, double-blind phase 3 trial in adults with obesity or overweight. It evaluates a regulated investigational programme, not PeptidsForm product equivalence.

Human evidenceOpen PubMed
HUMAN · SUBSTUDY

Tirzepatide

Body-composition changes in SURMOUNT-1

Diabetes, Obesity and Metabolism · PMID 39996356

A DXA substudy assessing changes in fat mass and lean mass. A substudy answers a narrower question than the parent trial and should be interpreted within that design.

Human evidenceOpen PubMed
PRECLINICAL · MECHANISTIC

MOTS-c

A mitochondrial peptide linked to metabolic homeostasis

Cell Metabolism · PMID 25738459

A foundational experimental study identifying MOTS-c and exploring metabolic effects in cellular and animal models. Preclinical findings are not evidence of clinical benefit in people.

Preclinical evidenceOpen PubMed
PRECLINICAL · MECHANISTIC

MOTS-c

Stress-dependent nuclear translocation of MOTS-c

Cell Metabolism · PMID 29983246

A mechanistic study examining how MOTS-c responds to metabolic stress and interacts with nuclear gene regulation. It develops a biological hypothesis rather than a clinical claim.

Preclinical evidenceOpen PubMed
HUMAN · PHASE 3 RCT

Retatrutide

Retatrutide monotherapy in type 2 diabetes

The Lancet · PMID 42250575

A randomised phase 3 study of retatrutide monotherapy in adults with type 2 diabetes. The publication reports trial outcomes; individual treatment decisions remain clinical matters.

Human evidenceOpen PubMed

EVIDENCE WITHOUT OVERSTATEMENT

Different sources answer different questions.

A study design determines how confidently a result can be interpreted and how far it can be generalised. Publication alone is not a quality stamp for every claim.

01RCT

Randomised human study

Tests predefined outcomes in participants under a controlled protocol. Relevance remains limited to the studied population, dose, comparator and duration.

02NCT

Official trial record

Documents the planned protocol, endpoints and status. A registry entry is not a published result and status can change.

03LAB

Mechanistic or preclinical study

Explores biological mechanisms in cells, tissues or animal models. It can support a hypothesis, but cannot establish human clinical benefit.

04LOT

Product and lot documentation

Research literature does not verify a specific vial. Product identity and analytical results must be linked to the exact lot through its own records.

RESEARCH CONTEXT

A molecule is not a product. A paper is not a prescription.

The library is an educational index of external sources. Inclusion does not imply endorsement, regulatory approval, product equivalence, clinical suitability or a claim that a PeptidsForm research format produced the published result.

See how a lot is verified

MOLECULE · EVIDENCE · LOT

Explore the molecule. Then verify the exact batch.

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